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Blog Details
Home > Blog >

Company blog about Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

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Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

2026-07-23

Combining sensitive longevity actives (NR, PQQ, Ergothioneine) with lipid compounds in a single formula is a major CDMO challenge due to active degradation and bad taste.

To solve this, KORNNAC Pharma engineered a showcase beadlet-in-oil liquid capsule—combining targeted 3-layer enteric micro-pellets with a cold-processed, aromatic lipid matrix.

The KORNNAC Pharma Solution: Dual-Phase Beadlet-in-Oil Innovation

To overcome these challenges, KORNNAC Pharma utilized our advanced liquid-filled capsule and 4.0 micro-pellet coating technologies to engineer a dual-phase delivery matrix.

Formulation Breakdown

Matrix Phase Active Ingredients & Dosage Engineering & Formulation Advantages

Solid Phase

(Pink Enteric Beadlets)

• NR (Nicotinamide Riboside): 100mg

• Ergothioneine: 25mg

• PQQ: 15mg

• Grape Seed Extract: 50mg

• 3-Layer Coating Armor: Shields NR from light, oxygen, and moisture to prevent hydrolysis.

• Taste Masking: Micro-seals PQQ to eliminate metallic bitterness.

• Enteric Acid Resistance: Escorts Ergothioneine safely past stomach acid for targeted intestinal release.

Liquid Phase

(Rose-Fraganced Red Liquid Matrix)

• Borage Oil (GLA): 350mg

• Lycopene: 0.5mg

• Astaxanthin: 0.5mg

• Rose Essential Oil: 1mg

• Cold-Processed Oil Lock: Preserves raw GLA activity without high-heat damage.

• Lipophilic Bioavailability: Lipid matrix optimizes absorption for Astaxanthin and Lycopene.

• Sensory & Clean Label: Subtle natural rose fragrance housed in a 100% plant-based HPMC shell.

3 Core Technical Advantages

  • Zero Cross-Contamination: Isolating 3-layer coated beadlets within the lipid matrix prevents solid moisture absorption and oil oxidation, drastically extending product shelf life.

  • Targeted Intestinal Delivery: Our enteric beadlets-in-capsule design bypasses stomach acid completely, releasing NR and Ergothioneine directly at pH 6.8 for maximum bioavailability.

  • Premium Visual & Sensory Appeal: Clear HPMC liquid capsules display vibrant pink beadlets in a ruby-red oil matrix, accompanied by a subtle rose aroma that boosts consumer repurchase rates.

Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

Scale Your Next Bestseller with KORNNAC Pharma

Whether you want to launch this exact anti-aging formula or develop a brand-new custom formula, KORNNAC Pharma provides complete contract manufacturing—from micro-pellet engineering to automated liquid-filled capsule sealing.

Contact KORNNAC Pharma today to request sample kits and start your custom liquid capsule project.

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Blog Details
Home > Blog >

Company blog about-Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

Events

News

Cases

Blog

Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

2026-07-23

Combining sensitive longevity actives (NR, PQQ, Ergothioneine) with lipid compounds in a single formula is a major CDMO challenge due to active degradation and bad taste.

To solve this, KORNNAC Pharma engineered a showcase beadlet-in-oil liquid capsule—combining targeted 3-layer enteric micro-pellets with a cold-processed, aromatic lipid matrix.

The KORNNAC Pharma Solution: Dual-Phase Beadlet-in-Oil Innovation

To overcome these challenges, KORNNAC Pharma utilized our advanced liquid-filled capsule and 4.0 micro-pellet coating technologies to engineer a dual-phase delivery matrix.

Formulation Breakdown

Matrix Phase Active Ingredients & Dosage Engineering & Formulation Advantages

Solid Phase

(Pink Enteric Beadlets)

• NR (Nicotinamide Riboside): 100mg

• Ergothioneine: 25mg

• PQQ: 15mg

• Grape Seed Extract: 50mg

• 3-Layer Coating Armor: Shields NR from light, oxygen, and moisture to prevent hydrolysis.

• Taste Masking: Micro-seals PQQ to eliminate metallic bitterness.

• Enteric Acid Resistance: Escorts Ergothioneine safely past stomach acid for targeted intestinal release.

Liquid Phase

(Rose-Fraganced Red Liquid Matrix)

• Borage Oil (GLA): 350mg

• Lycopene: 0.5mg

• Astaxanthin: 0.5mg

• Rose Essential Oil: 1mg

• Cold-Processed Oil Lock: Preserves raw GLA activity without high-heat damage.

• Lipophilic Bioavailability: Lipid matrix optimizes absorption for Astaxanthin and Lycopene.

• Sensory & Clean Label: Subtle natural rose fragrance housed in a 100% plant-based HPMC shell.

3 Core Technical Advantages

  • Zero Cross-Contamination: Isolating 3-layer coated beadlets within the lipid matrix prevents solid moisture absorption and oil oxidation, drastically extending product shelf life.

  • Targeted Intestinal Delivery: Our enteric beadlets-in-capsule design bypasses stomach acid completely, releasing NR and Ergothioneine directly at pH 6.8 for maximum bioavailability.

  • Premium Visual & Sensory Appeal: Clear HPMC liquid capsules display vibrant pink beadlets in a ruby-red oil matrix, accompanied by a subtle rose aroma that boosts consumer repurchase rates.

Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

Scale Your Next Bestseller with KORNNAC Pharma

Whether you want to launch this exact anti-aging formula or develop a brand-new custom formula, KORNNAC Pharma provides complete contract manufacturing—from micro-pellet engineering to automated liquid-filled capsule sealing.

Contact KORNNAC Pharma today to request sample kits and start your custom liquid capsule project.

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