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Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

2026-07-23

Combining sensitive longevity actives (NR, PQQ, Ergothioneine) with lipid compounds in a single formula is a major CDMO challenge due to active degradation and bad taste.

To solve this, KORNNAC Pharma engineered a showcase beadlet-in-oil liquid capsule—combining targeted 3-layer enteric micro-pellets with a cold-processed, aromatic lipid matrix.

The KORNNAC Pharma Solution: Dual-Phase Beadlet-in-Oil Innovation

To overcome these challenges, KORNNAC Pharma utilized our advanced liquid-filled capsule and 4.0 micro-pellet coating technologies to engineer a dual-phase delivery matrix.

Formulation Breakdown

Matrix Phase	Active Ingredients & Dosage	Engineering & Formulation Advantages
Solid Phase (Pink Enteric Beadlets)	• NR (Nicotinamide Riboside): 100mg • Ergothioneine: 25mg • PQQ: 15mg • Grape Seed Extract: 50mg	• 3-Layer Coating Armor: Shields NR from light, oxygen, and moisture to prevent hydrolysis. • Taste Masking: Micro-seals PQQ to eliminate metallic bitterness. • Enteric Acid Resistance: Escorts Ergothioneine safely past stomach acid for targeted intestinal release.
Liquid Phase (Rose-Fraganced Red Liquid Matrix)	• Borage Oil (GLA): 350mg • Lycopene: 0.5mg • Astaxanthin: 0.5mg • Rose Essential Oil: 1mg	• Cold-Processed Oil Lock: Preserves raw GLA activity without high-heat damage. • Lipophilic Bioavailability: Lipid matrix optimizes absorption for Astaxanthin and Lycopene. • Sensory & Clean Label: Subtle natural rose fragrance housed in a 100% plant-based HPMC shell.

Matrix Phase

Active Ingredients & Dosage

Engineering & Formulation Advantages

Solid Phase

(Pink Enteric Beadlets)

• NR (Nicotinamide Riboside): 100mg

• Ergothioneine: 25mg

• PQQ: 15mg

• Grape Seed Extract: 50mg

• 3-Layer Coating Armor: Shields NR from light, oxygen, and moisture to prevent hydrolysis.

• Taste Masking: Micro-seals PQQ to eliminate metallic bitterness.

• Enteric Acid Resistance: Escorts Ergothioneine safely past stomach acid for targeted intestinal release.

Liquid Phase

(Rose-Fraganced Red Liquid Matrix)

• Borage Oil (GLA): 350mg

• Lycopene: 0.5mg

• Astaxanthin: 0.5mg

• Rose Essential Oil: 1mg

• Cold-Processed Oil Lock: Preserves raw GLA activity without high-heat damage.

• Lipophilic Bioavailability: Lipid matrix optimizes absorption for Astaxanthin and Lycopene.

• Sensory & Clean Label: Subtle natural rose fragrance housed in a 100% plant-based HPMC shell.

3 Core Technical Advantages

Zero Cross-Contamination: Isolating 3-layer coated beadlets within the lipid matrix prevents solid moisture absorption and oil oxidation, drastically extending product shelf life.
Targeted Intestinal Delivery: Our enteric beadlets-in-capsule design bypasses stomach acid completely, releasing NR and Ergothioneine directly at pH 6.8 for maximum bioavailability.
Premium Visual & Sensory Appeal: Clear HPMC liquid capsules display vibrant pink beadlets in a ruby-red oil matrix, accompanied by a subtle rose aroma that boosts consumer repurchase rates.

Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

Scale Your Next Bestseller with KORNNAC Pharma

Whether you want to launch this exact anti-aging formula or develop a brand-new custom formula, KORNNAC Pharma provides complete contract manufacturing—from micro-pellet engineering to automated liquid-filled capsule sealing.

Contact KORNNAC Pharma today to request sample kits and start your custom liquid capsule project.

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Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

2026-07-23

Combining sensitive longevity actives (NR, PQQ, Ergothioneine) with lipid compounds in a single formula is a major CDMO challenge due to active degradation and bad taste.

To solve this, KORNNAC Pharma engineered a showcase beadlet-in-oil liquid capsule—combining targeted 3-layer enteric micro-pellets with a cold-processed, aromatic lipid matrix.

The KORNNAC Pharma Solution: Dual-Phase Beadlet-in-Oil Innovation

To overcome these challenges, KORNNAC Pharma utilized our advanced liquid-filled capsule and 4.0 micro-pellet coating technologies to engineer a dual-phase delivery matrix.

Formulation Breakdown

Matrix Phase	Active Ingredients & Dosage	Engineering & Formulation Advantages
Solid Phase (Pink Enteric Beadlets)	• NR (Nicotinamide Riboside): 100mg • Ergothioneine: 25mg • PQQ: 15mg • Grape Seed Extract: 50mg	• 3-Layer Coating Armor: Shields NR from light, oxygen, and moisture to prevent hydrolysis. • Taste Masking: Micro-seals PQQ to eliminate metallic bitterness. • Enteric Acid Resistance: Escorts Ergothioneine safely past stomach acid for targeted intestinal release.
Liquid Phase (Rose-Fraganced Red Liquid Matrix)	• Borage Oil (GLA): 350mg • Lycopene: 0.5mg • Astaxanthin: 0.5mg • Rose Essential Oil: 1mg	• Cold-Processed Oil Lock: Preserves raw GLA activity without high-heat damage. • Lipophilic Bioavailability: Lipid matrix optimizes absorption for Astaxanthin and Lycopene. • Sensory & Clean Label: Subtle natural rose fragrance housed in a 100% plant-based HPMC shell.

Matrix Phase

Active Ingredients & Dosage

Engineering & Formulation Advantages

Solid Phase

(Pink Enteric Beadlets)

• NR (Nicotinamide Riboside): 100mg

• Ergothioneine: 25mg

• PQQ: 15mg

• Grape Seed Extract: 50mg

• 3-Layer Coating Armor: Shields NR from light, oxygen, and moisture to prevent hydrolysis.

• Taste Masking: Micro-seals PQQ to eliminate metallic bitterness.

• Enteric Acid Resistance: Escorts Ergothioneine safely past stomach acid for targeted intestinal release.

Liquid Phase

(Rose-Fraganced Red Liquid Matrix)

• Borage Oil (GLA): 350mg

• Lycopene: 0.5mg

• Astaxanthin: 0.5mg

• Rose Essential Oil: 1mg

• Cold-Processed Oil Lock: Preserves raw GLA activity without high-heat damage.

• Lipophilic Bioavailability: Lipid matrix optimizes absorption for Astaxanthin and Lycopene.

• Sensory & Clean Label: Subtle natural rose fragrance housed in a 100% plant-based HPMC shell.

3 Core Technical Advantages

Zero Cross-Contamination: Isolating 3-layer coated beadlets within the lipid matrix prevents solid moisture absorption and oil oxidation, drastically extending product shelf life.
Targeted Intestinal Delivery: Our enteric beadlets-in-capsule design bypasses stomach acid completely, releasing NR and Ergothioneine directly at pH 6.8 for maximum bioavailability.
Premium Visual & Sensory Appeal: Clear HPMC liquid capsules display vibrant pink beadlets in a ruby-red oil matrix, accompanied by a subtle rose aroma that boosts consumer repurchase rates.

Case Study: How KORNNAC Pharma Engineered a Next-Gen Anti-Aging Beadlet-in-Oil Liquid Capsule

Scale Your Next Bestseller with KORNNAC Pharma

Contact KORNNAC Pharma today to request sample kits and start your custom liquid capsule project.

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Sea Buckthorn Seed Oil Capsule

Capsule In Capsule

Custom Capsules

Gut Health Capsule

Beauty Capsule

Sleep Capsule

Weight Control Capsule

Women's Health Capsule

Immune Defense Capsule

Joint Support Capsule

Cognitive Function Capsule

Cardio & Bone Capsule

Energy & Metabolism Booster Capsule

Cellular Longevity & Antioxidant Capsule

Beadlets In Liquid Capsule

Custom Capsules

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Stress Capsule

Sport Capsule

Beauty & Skin Capsule

Joint Support Capsule

Women's Health Capsule